KMSS is responsible to implement HIV/AIDS Prevention Program with different high risk groups since 2000 and presently implements three National Programs for Drug Users (IDUs), MSM & Hijra’s & HIV Intervention at 2 Prison’s aiming harm reduction as well as HIV/AIDS prevention for those who are most vulnerable for spreading HIV/AIDS in Bangladesh.
KMSS is operating a national project at Khulna, Bagerhat, Jessore and Satkhira Municipal Area named "Expanding Provision of Essential Harm Reduction Services for IDUs (GF#907)" funded by Global Fund, managed and monitor by Save the Children and NASP through implementing nine DICs (three in Khulna, two at Bagerhat and Mongla, one at Jessore, one at Benapole & other one at Satkhira) started from April'08 & June’12 respectively. The said project has been handed over to SCI on March’2013 following successful completion of contact period.
The second Project is named as “Expanding HIV Prevention in Bangladesh among MSM & Hijra, RCC Program, Round-2 funded by Global Fund and managed by NASP & ICDD’B. KMSS is implementing this project through 4 Drop-in-Centers (DIC). Out of 4 DIC’s two is located at Khulna and rest of them are at Begerhat & Mongla respectively. Through these 4 DIC’s KMSS is serving 1654 MSM’s 586 Hijra's.
The third one is “Prevention of the Spread of HIV in Prisons in South Asia, RAS, H-71”, which is operating in Khulna and Jessore Prison, funded by UNODC, started from December’ 2011. Through this project, KMSS is covering all Prison Officials and near about 2500 inmates.
At January 2013 KMSS started HIV/AIDS Prevention Services (HAPS), SP-3 & SP-5 through operating 3 DICs, 2 at Rajshahi & 1 at Bogra aiming Hotel and Residence based Sex Workers, MSM & Transgender which is funded by World Bank, Managed by Ministry of Health and Family Welfare (MoHFW) and NASP.
To be noted here that, KMSS is one of the few organizations in Bangladesh who has experienced of working with all high risk groups of Bangladesh vulnerable to HIV/AIDS.